Pulmonary & Respiratory Medicine

Major factors of lung problems

Over the next years, the number of extremely preterm newborns who survive into childhood will continue to rise, which will likely lead to an increase in the number of kids with chronic lung diseases. Nutritional deficits and maternal smoking both have an epigenetic impact on the developing lungs, and prenatal variables are known to affect lung health later in life. These epigenetic elements even appear to have impacts that span generations, from the grandmother to the mother to the daughter. As infants with cystic fibrosis or neuromuscular illness benefit from early intervention with novel focused biological techniques, life expectancy for a number of congenital abnormalities has also increased significantly with improved care.

Genetic and epigenetic factors connected to the environment affect lung development in addition to altering defense mechanisms. An excessive inflammatory response to common allergens results in allergies in the form of rhinitis or asthma of varying severity, which frequently last into adulthood. To enhance the present treatments, a deeper comprehension of these pathways is still required.